4. Sara Ramirez
Rank last year: 4
We’ve been lucky enough to see Sara Ramirez play Callie Torres every Thursday night since 2006, and it didn’t take long for us to fall for them both. As Callie on Grey’s Anatomy, Ramirez plays a doctor with strong convictions in both her personal and professional lives. In reality, she’s a woman who supports her character’s bisexuality, and dazzled us with her singing talent on her debut EP this year. But it is on the ABC show that Ramirez really shines, with recent musical and wedding episodes focusing on her and her on-screen wife (played by Jessica Capshaw). Her performance of Brandi Carlile’s “The Story” on Grey’s Anatomy gave us chills, and turned out to be one of the most lesbian moments ever seen on TV.