Wanda Sykes I’ma Be Me (HBO Comedy 2:05 a.m.) — If you haven’t seen Sykes’ now infamous standup special, punch yourself in the face! Or, you know, tune in.
Biography "The Facts of Life" (Bio 4 a.m.) — You’ve read the fanfic, now go behind the scenes.
The O.C. "The Rainy Day Women" (SoapNet 1 p.m.) — The Alex/Marissa storyline continues. Marissa tells her mom about her new relationship and moves in with Alex.
Grey’s Anatomy "Losing My Mind" (Lifetime 1 p.m.) — The Callie/Erica stroyline begins. Lifetime will be airing episodes at 1:00 and 2:00 all week.
Ghost Whisperer "Slam" (Ion 3 p.m.) — A lesbian high schooler confronts the ghost of her overprotective brother. Her love interest is played by Brie Larson from United States of Tara.
Flipping Out "Bright Lewis, Big City" (Bravo 9 p.m.) — One of the houses Jeff is remodeling this season is owned by a lesbian couple.
White Collar "Point Blank" (USA 9 p.m.) — The summer finale. Diana, what is up with that music box?
Margaret Cho on Late Night with Jimmy Fallon — The out comedian talks about her new album, Cho Dependent.
The O.C. "The Mallpisode" (SoapNet 1 p.m.) — Marissa spends the night with her friends, including Ryan, locked in the mall, and lies to Alex about it.
Law & Order "For Love or Money" (TNT 4 p.m.) — KateMoennig guest stars as the daughter of a wealthy widow (Cathy Moriarty)who is involved in the death of a parolee.
Eve "Girlfriends" (TV One 7:30 p.m.) — Shelly and Janie try to get Rita (Ali Landry) to pretend she wants to get back together with Brenda after learning she’s the buyer for a department store where they hope to display their clothing line.
Biography "Jodie Foster" (Bio 8 p.m.) — The 2005 biography follows the life of Foster from child star to adulthood.
America’s Next Top Model "Welcome to High Fashion" (CW 8 p.m.) — Features lesbian contestant Kayla.
Hellcats "A World Full of Strangers" (CW 9 p.m.) — The premiere of CW’s new teen drama features lesbian cheerleader Patty.
Rick & Steve: The Happiest Gay Couple in All the World (Logo 12p.m.) — A seven episode marathon of the hilarious animated comedy featuring lesbian couple Kirsten and Dana, and the voice of Margaret Cho.
The O.C. "The Blaze of Glory" (SoapNet 1 p.m.) — The disastrous final episode of the Alex/Marissa storyline, wherein Alex suddenly becomes a violent crazy person. It is the ultimate lesbian Sweeps finale.
What I Like About You "How to Succeed in Business Without Really Trying to Be a Lesbian" (TeenNick 2:30 p.m.) — Holly leads her new, lesbian boss to believe she, too, is gay so she won’t get fired. Meanwhile, Val bonds with a lesbian (Jenny McCarthy) who is also gettingover a failed relationship.
Stand Up to Cancer (Network TV, 8 p.m.) — Queen Latifah is one of the many celebrities participating in the fundraiser for cancer research.
iCarly "iSam’s Mom" (Nick 8 p.m.) – Jane Lynch guest stars as Sam’s mom.
The Rachel Maddow Show, week nights at 9:00 on MSNBC.
Issues with Jane Valez-Mitchell, nightly at 7:00 on CNN’s Headline News.
The Suze Orman Show, Saturdays at 5 a.m., 9 p.m., and 12 a.m. on CNBC.
The Ellen DeGeneres Show, daytime weekdays.
As always, thanks to roni1133 for her lesbian TV expertise!